Update - Tramadol & the WADA 2024 Prohibited List - International Testing Agency (2024)

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1 December 2023

From 1 January 2024, Tramadol will be prohibited in-competition in sport. Do you know if or how this addition to the Prohibited List may affect you?

What is tramadol?

Tramadol is a synthetic opioid pain medication used to treat moderate-to-severe pain. It is sometimes used to treat pain due to sports injuries in athletes. It is in the category of “Narcotics” on the Prohibited List.

Tramadol is available in many different formulations, and is sold under many various brand names in different countries. Examples of brand names include: Tramal, Tramedo, Tramake, Zydol. Many other brand names exist and so athletes should check with their doctor or pharmacist what brands are prescribed in their own countries.

Update - Tramadol & the WADA 2024 Prohibited List - International Testing Agency (2)

How does a substance get added to the Prohibited List?

The World Anti-Doping Agency (WADA) has a group of experts that decides which substances are to be included in the Prohibited List. For a substance to be placed on the Prohibited List it must meet two of the three following criteria:

  • It has the potential to enhance or enhances performance, alone or in combination with other substances or methods;
  • It represents an actual or potential health risk to the athlete;
  • It violates the spirit of sport

Update - Tramadol & the WADA 2024 Prohibited List - International Testing Agency (3)

Which criteria does tramadol meet?

Recent studies have confirmed the potential to enhance physical performance in certain activities. Read one of the studies here: Is tramadol a performance enhancing drug?

Tramadol use has potential health risks for athletes. It can result in serious side effects, which include addiction and physical dependence, seizures and decreased alertness.

Use of tramadol is also against the spirit of sport.

Curious to know more about the rational behind the decision to prohibit tramadol or other substances in-competition? See page 4 of this document, WADA’s Summary of Major Modifications and Explanatory Notes.

When is tramadol banned?

Tramadol is prohibited during the in-competition period unless the Athletes have a Therapeutic Use Exemption (TUE).

What is the In-Competition period?

The in-competition period usually begins at 11:59pm on the night before competition, but always check your International Federation’s (IF) Anti-Doping Rules.

Is there a washout period for tramadol?

Tramadol is prohibited during the In-Competition period (which starts from 11:59 pm the evening before your competition). If you require tramadol for a medical reason during the In-Competition period, you must apply for a TUE.

Based on excretion studies, WADA has stated that the washout period for Tramadol is 24 hours. This is the time it should take after the last therapeutic dose for tramadol to get out of your system to a level that should not result in a positive test (also known as an Adverse Analytical Finding). If you need tramadol for a medical reason close to the 24 hours before the In-Competition period, be aware that you may test positive for tramadol, and may need to provide medical records to explain this if you do and request a retroactive TUE. For this reason, it is important for your doctor to keep accurate records of the dose and time of tramadol administration.

Use of tramadol for urgent or emergency treatment of pain

Sometimes tramadol is required to be prescribed and administered to athletes for the urgent or emergency treatment of pain, such as when a severe, painful injury occurs during sport. When required for urgent or emergency treatment during the in-competition period, a Retroactive TUE should be applied for. It is therefore important that your doctor keeps good medical records of tramadol administration as it will be needed for this purpose.

I’m an athlete and I sometimes take tramadol for pain: what do I need to do?

Tell your doctor that tramadol is banned in-competition in sport. Ask them to consider your treatment options and possible alternatives.

If you require tramadol for your condition, ask your doctor to support you in submitting a TUE application. This may be a “Retroactive TUE” if tramadol was needed urgently for emergency treatment.

Understand the process around TUEs and whether you need one. Make sure you follow the necessary steps and have the required medical documentation. The  ITA Athlete Hub is an excellent resource for more information on these topics.

Consequences of taking prohibited substances

The consequences of a positive test for a substance on the Prohibited List can be wide-ranging, with potential serious adverse effects to your health, sanctions from competing in your sport which will impact your sporting career, social and family network and potentially your finances. More precisely, the presence of Tramadol in a sample provided in-competition, for which a TUE is not granted, leads to a period of Ineligibility which may go up to two years and disqualification of competition results.

You can find two interesting webinars on the ITA YouTube channel about the consequences of doping. Check out this playlist, or watch them directly below

USEFUL RESOURCES

Monthly Webinar – Consequences of Doping Part 1: Impact on emotions

Monthly webinar – Consequences of Doping Part 2: Effects on others

Update - Tramadol & the WADA 2024 Prohibited List - International Testing Agency (2024)

FAQs

Update - Tramadol & the WADA 2024 Prohibited List - International Testing Agency? ›

World Anti-Doping Agency Releases 2024 Banned Substance List: Tramadol Now Banned In-Competition.

Will tramadol be banned in 2024? ›

World Anti-Doping Agency Releases 2024 Banned Substance List: Tramadol Now Banned In-Competition.

Is tramadol on the WADA prohibited list? ›

The narcotic tramadol is prohibited in-competition

Tramadol is an opioid used to treat moderate to severe pain. Before 2024, tramadol was on a list of substances and methods that WADA was monitoring (Monitoring Program) to gather data on whether athletes could be using it.

Is tramadol on the banned list? ›

Tramadol is a synthetic opioid pain medication used to treat moderate-to-severe pain. It is sometimes used to treat pain due to sports injuries in athletes. It is in the category of “Narcotics” on the Prohibited List.

What is the 2024 prohibited list? ›

The 2024 Prohibited List is one of the eight International Standards that are mandatory for all Signatories of the World Anti-Doping Code (Code). It designates what substances and methods are prohibited both in- and out-of-competition and which substances are banned in particular sports.

Will tramadol become a prohibited substance in the New Year? ›

Particular attention should be given to information regarding tramadol: in September 2022, WADA decided to prohibit the narcotic tramadol in competition, effective January 1, 2024.

Has tramadol been recalled? ›

The Harvard Drug Group is recalling 3876 cartons of tramadol hydrochloride tablets because of a packaging defect. According to the July 5, 2023, US Food and Drug Administration (FDA) Enforcement Report, the product's blister packaging is inadequately sealed.

Is Ultram ER being discontinued? ›

The Ultram ER brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

Why is tramadol banned in Canada? ›

Tramadol abuse, with its dose-dependent risks of physical dependence, opiate use disorder, and overdoses in the general population, is of concern and has led to it being a controlled drug in many countries, including Canada.

Is tramadol a controlled substance DEA? ›

The Drug Enforcement Administration (DEA), the Centers for Disease Control and Prevention (CDC) and the Ultram® package insert indicate that tramadol is a controlled substance which contains an opioid. Links to the supporting documentation is provided below.

Is tramadol 377 a controlled substance? ›

Tramadol is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

Why was tramadol recalled? ›

Teva Pharmaceuticals USA is recalling more than 2 million bottles of 50-mg tramadol hydrochloride tablets because they contain an incorrect package insert.

Is tramadol from 2014 still good? ›

Do not use ARROW - TRAMADOL after the expiry date printed on the pack. If you take this medicine after the expiry date has passed, it may not work as well.

Why was tramadol changed to a controlled substance? ›

Tramadol (ConZip) is an opioid pain medication that was FDA-approved in 1995. At first, tramadol was a non-controlled medication. This means it could be prescribed by healthcare providers with few restrictions. But some medical experts became concerned about the potential for tramadol dependence and misuse.

Why is tramadol banned by the UCI? ›

The UCI did not want to enter the debate on sporting performance for the time being and decided to ban Tramadol for the safety of the cyclists themselves. The adverse effects of Tramadol include nausea, inattention and drowsiness. This increases the risk of accidents.

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