Northern, Southern Italian Populations Began to Diverge Genetically Thousands of Years Ago (2024)

\NEW YORK – Northern and southern Italian populations began to diverge genetically thousands of years ago, according to a new study.

Researchers from the University of Bologna sequenced the genomes of more than three dozen unrelated individuals from northern and southern Italy and compared their genomes, not only to each other but also to the genomes of other populations, including ancient populations. The Italian population is thought to reflect on a smaller scale the biological and demographic processes that shaped the wider European population, the researchers noted.

Through their analysis, the researchers uncovered genetic differences between northern and southern Italian populations. While some of these differences reflect the varying influence of outside populations on Italians, they also revealed what appear to be specific biological adaptations to the two regions of Italy that influence obesity and melanoma susceptibility. These factors all combined to shape the Italian population, as the researchers reported on Thursday in BMC Biology.

"When comparing sequences between modern and ancient genome samples, we found early genetic divergence between the ancestors of northern and southern Italian groups dating back to the Late Glacial, around 19,000 to 12,000 years ago," lead author Marco Sazzini from the University of Bologna said in a statement. "Migrations during the Neolithic and Bronze Age periods, thousands of years later, then further differentiated their gene pools."

For their analysis, the researchers generated whole-genome sequencing data on 38 individuals from different regions of Italy whose families had lived there for generations. These individuals represented the extreme ends of the clines between the northern and southern Italian populations.

When they compared these two populations to other modern populations, the researchers found varying influences. Both Italian populations shared similar portions of their DNA with Sardinians and northern Caucasian populations. These two groups, the researchers noted, are thought to reflect the early Neolithic and Bronze Age contributions to the ancestral pan-European genetic background. At the same time, southern Italians shared about 30 percent of their DNA with Near Eastern populations, while northern Italians share little, if any DNA, with Near Eastern populations. Instead, northern Italians shared more of their genetic background with Eastern and Northern European groups and the Basque.

Similarly, after adding in previously published data from ancient individuals, the researchers found that southern Italians shared more genetic ancestry with Chalcolithic/Bronze Age and Neolithic individuals from Anatolia, Armenia, the Near East, and Greece, while northern Italians shared more genetic ancestry Western Europeans dating back to the Copper Age.

The researchers estimated that northern and southern Italians began to diverge thousands of years ago, during the late Glacial Maximum, noting that southern Italy has been proposed to have served as a refuge for people during that time.

Later, northern and southern Italians began to diverge further, and the researchers uncovered differing regions of the genome that are under positive or balancing selection in one population, but not the other.

In northern Italians, the researchers teased out a signal of selection involving the ADCY genes, which help regulate thermogenesis and adiposity as well as influence susceptibility to diabetes and obesity. The researchers speculate that this may have enabled northern Italians to adapt to lower environmental temperatures and high-calorie diets and could now account for the lower rate of diabetes seen in northern Italians, as compared to southern Italians.

Southern Italians, meanwhile, appeared to have a signal of selection affecting the mucin gene C1GALT1, which may represent an adaptation to microorganisms in region, and one affecting the FZD/Wnt genes involved in melanin production, which could account for the lower rate of melanoma now seen in southern Italians, as compared to northern Italians.

"Further research in this area may help us understand how the observed genetic differences can impact population health or predisposition to a number of diseases," Sazzini added.

Northern, Southern Italian Populations Began to Diverge Genetically Thousands of Years Ago (2024)

FAQs

Did northern southern Italian populations began to diverge genetically thousands of years ago? ›

The research suggests that northern and southern Italian populations may have begun to diverge genetically as early as 19,000-12,000 years ago and constitutes the earliest known evidence of genetic divergence in Italy so far.

What are the genetic differences between northern and Southern Italians? ›

According to the PCA plot, also in the ADMIXTURE analysis there are relatively small differences in ancestry between Northern Italians and Central Italians while Southern Italians showed a lower average admixture NE proportion (44%) than Northern and Central Italy, and a higher Caucasian ancestry of 28%.

Why is Northern Italy so different from southern Italy? ›

The gap between the North and the South can be explained via history. Arabs, Greeks and Spanish people reigned in southern Italy, while French, Celtic and Germanic tribes reigned in the north. For this reason, the culture, customs and cuisine have been strongly influenced by these different countries.

Why is there a divide between north and south Italy? ›

Though the ultimate causes are contested, economic historians agree that a key proximate cause of Italy's North-South divide is the uneven spread of industry, which is concentrated in the North.

When did north and South Italy divide? ›

Starting from the unification of Italy in 1861–1870, a growing economic divide between the northern provinces and the southern half of Italy became evident.

When did northern and southern Italy unite? ›

Proclamation of the Kingdom of Italy, 1861.

Garibaldi's march to “liberate” the Kingdom of the Two Sicilies in 1860 brought the southern peninsula into the fold, and the new Kingdom of Italy was proclaimed on March 17, 1861, with the royal family of Piedmont-Sardinia as the new ruling monarchs of Italy.

What are 3 key differences between northern and southern Italian food? ›

Italians from the northern part of the country love rich cream sauces, stuffed meats, and savory polenta, Italians from the south prefer light olive oils, fresh steamed seafood and of course tangy tomato sauce.

What is the difference between the foods of northern Italy and southern Italy? ›

Southern Italy is more heavily reliant on seafood and lamb compared to Northern Italy which utilizes a combination of beef, lamb, pork, and seafood.

What are some differences and similarities between northern and southern Italy? ›

South Italy focuses heavily in agriculture and tourism while the North is more industrial. Both North and South Italy have tourism as an industry. The difference between food in the North and South of Italy is that the food is richer and butter and cream are more common in the North.

What's the difference between northern and Southern Italians? ›

There is a stereotype that Northern Italians tend to be more hardworking and business-oriented, but can also be quite snobbish. For Southern Italians, they are thought to be more laid back but could become borderline lazy.

What are the major economic differences between northern and southern Italy? ›

North Italy is massively richer than the South for several reasons. The North is characteristically wealthy with a prosperous trade, industrial economy, and developed tourist infrastructure. Milan is the wealthiest city in Italy, and living expenses and income are almost twice that of the south.

Why is the south of Italy so different from the north of Italy quizlet? ›

Why is the south of Italy so different from the north of Italy? The south suffers from economic disarray, corruption, and state-run activities. The majority of the Western European agriculture takes place on the Great European Plain. The climate of Western Europe is a predominantly a marine climate.

Why is the North South divide a problem? ›

This creates a large wealth divide, and those living in the north of the country can experience lower incomes, higher unemployment and a lower standard of living than those living in the south.

Is Italy still divided north and south? ›

The Italian vote is no longer divided between left and right, but between north and south.

Where did the North South divide come from? ›

The Economist proposed in a 2017 article that the origins of the north–south divide could be traced back to the Norman Conquest, and the Harrying of the North in which William the Conqueror laid waste to many towns and estates in the North.

What is the history of the North south divide in Italy? ›

The north-south divide throughout Italy dates back centuries before Italian unification when the south was separated by city-states known as “The Kingdom of the Two Sicilies.” Southern Italy was predominantly settled by Greeks, Normans, and Lombards who emigrated in mass numbers from their home countries.

Who joined southern and northern Italy? ›

Giuseppe Garibaldi joined southern Italy to northern Italy. The Papal States (including Rome) became the last to join Italy.

Why was Italy so divided in the Middle Ages? ›

High Medieval Northern Italy was further divided by the long running battle for supremacy between the forces of the papacy and of the Holy Roman Empire. Each city aligned itself with one faction or the other, yet was divided internally between the two warring parties, Guelfs and Ghibellines.

When did northern Italians come to America? ›

Between 1820 and 1870, fewer than 25,000 Italian immigrants came to the U.S., mostly from northern Italy. These early arrivals settled in communities all across the country, from the farm towns of New Jersey and the vineyards of California to the ports of San Francisco and New Orleans.

When did Italy switch sides? ›

On October 13, 1943, the government of Italy declares war on its former Axis partner Germany and joins the battle on the side of the Allies.

Who conquered northern Italy? ›

The Lombards were joined by numerous Saxons, Heruls, Gepids, Bulgars, Thuringians and Ostrogoths, and their invasion of Italy was almost unopposed. By late 569, they had conquered all of northern Italy and the principal cities north of the Po River except Pavia, which fell in 572.

Do they eat pizza in Northern Italy? ›

One of Rome's typical street foods for example – yet easy to find in other locations, mostly in Northern Italy but also in Sicily – is the pizza al taglio: a sort of 'pizza by the slice' more similar to a focaccia, baked in rectangular trays, sold in cut pieces and priced based on weight.

What is Northern Italian food known for? ›

In addition to the ubiquitous pasta, Northern Italian cuisine uses staples such as rice and corn, featured in risotto and polenta.

What were the two main differences between the northern and Italian Renaissance? ›

The Italian Renaissance writers focused on secular concerns and advancing the individual, while Northern Renaissance writers focused on reforming society based on Christian principles. Both movements were similar because they were based on humanistic studies of ancient Greek and Roman writers.

Is it better to live in northern or southern Italy? ›

The north has a high concentration of famous cities but also encompasses some of the best natural areas such as lakes and mountains. The south on the other hand is more laid-back, and affordable and has extremely fresh food, lots of countrysides and great beaches.

Is there a difference between Italians and Sicilians? ›

One of the biggest difference between Sicilians and Italians is that the former is an autonomous region while the latter is comprised of 20 different regions. In other words, Sicily is its own country within a country.

What meat do Italians eat the most? ›

Pork in all – and we mean all – of its forms

It's no secret that Italians are big pork eaters, but pork actually goes into a lot of Italy's most esoteric cuisine. In fact, some of the most famous regional dishes use some of the strangest cuts of pork.

What are the main differences between the northern and southern states? ›

Economic practices, religious practices, education, cultural differences, and political differences all furthered the division between the North and South about the institution of slavery.

How do the physical characteristics of southern Italy differ from those of northern Italy? ›

The physical characteristics of northern Italy differs from southern Italy because it is a major agricultural and industrial center. Northern Italy is powered by the rivers in the Alps provide hydroelectricity and the Alps contain ski resorts.

What were the similarities and differences between northern and southern societies? ›

The North and South both had lots of characteristics that were similar such as discrimination against African Americans, reliance on cotton, and the growth of factories in some large cities. The North and South also had a lot of differences such as their transportation, geography, and economical growth.

What is the difference between northern and southern Italian accents? ›

Northerners tend to have open vowels. Southerners tend to use closed vowels. That's not the common rule, as there are parts of Southern Italy using vowels way more open than the Northern ones, so it is a matter of specific location rather than bigger areas, but, on the whole, that's it.

What are the climate differences between north and south Italy? ›

Between the north and south there can be a considerable difference in temperature, above all during the winter: on some winter days it can be −2 °C (28 °F) and snowing in Milan, while it is 8 °C (46.4 °F) in Rome and 20 °C (68 °F) in Palermo. Temperature differences are less extreme in the summer.

Is southern Italy hotter than northern Italy? ›

If you're wondering what is Italy weather like when you go to its south, it is customarily warmer than in the north.

What are at least two main economic differences between the northern and the southern states? ›

The North produced 17 times more cotton and woolen textiles than the South, 30 times more leather goods, 20 times more pig iron, and 32 times more firearms. The North produced 3,200 firearms to every 100 produced in the South.

How did the northern and southern economies develop differently and why? ›

The north had a much more industrial revolutionized approach toward their lifestyle, while the south was more inclined with slave -labor. The north made a living from industrial lifestyles rapidly producing many products like textiles, sewing machines, farm equipment, and guns.

What was the main difference between the economy of the southern colonies and the northern colonies? ›

The southern colonies had large plantations that grew tobacco or cotton and required slave labor, while northern colonies had small family farms. Learn more about the economics of the 13 British colonies with these classroom resources.

What was the difference between the Italy city-states and most of the rest of Europe leading to an intellectual revolution? ›

While cities were emerging in northern Italy, the rest of Europe remained mostly rural. It is in cities where people have better opportunities to exchange new ideas, creating an ideal breeding ground for an intellectual revolution.

What made the Italian city-states unique and important compared to other European cities before the Renaissance period? ›

Why were they important? The wealth of the Italian city-state played an important role in the Renaissance. This wealth allowed prominent families to support artists, scientists, and philosophers spurring on new ideas and artistic movements.

What is the difference between food in the north and south of Italy how does the climate affect this? ›

The climate also affects the types of food and plants that grow in Italy. Some plants, like olive trees grow better in warm weather. Olive trees do not grow well in the northern areas where it is cold. In the south olive oil is used while in the north butter and lard are used in place of olive oil.

Why is there a north-south divide in Italy? ›

Though the ultimate causes are contested, economic historians agree that a key proximate cause of Italy's North-South divide is the uneven spread of industry, which is concentrated in the North.

What is the North-South divide and how can it be solved? ›

The north-south divide is a term used to describe the social, economic and cultural disparities between the London and the south-east of England and the rest of the UK. People living in the south-east typically have a longer life expectancy, higher income and better standard of living than those living in the north.

Does the North-South divide still exist? ›

Existence. The North–South divide is not an exact line, but one that can involve many stereotypes, presumptions and other impressions of the surrounding region relative to other regions. The existence of the North–South divide is fiercely contested.

When did North and south Italy divide? ›

Starting from the unification of Italy in 1861–1870, a growing economic divide between the northern provinces and the southern half of Italy became evident.

When did North and south Italy unify? ›

Yet, the idea of the Risorgimento continued to gain adherents after 1848. The final push for Italian unification came in 1859, led by the Kingdom of Piedmont-Sardinia (then the wealthiest and most liberal of the Italian states), and orchestrated by Piedmont-Sardinia's Prime Minister, Count Camillo di Cavour.

When was Italy split in two? ›

From the year 568 AD all the way until the late 19th century, Italy was divided. Measured on this time scale, the movement to unify Italy — dating from about 1815 to 1870 — happened at light speed.

What is the North south divide theory? ›

The north becomes synonymous with economic development and industrialization while the South represents the previously colonized countries which are in need of help in the form of international aid agendas. In order to understand how this divide occurs, a definition of "development" itself is needed.

What is the North south divide now known as? ›

The concept of Global North and Global South (or North–South divide in a global context) is used to describe a grouping of countries along the lines of socio-economic and political characteristics.

Who are southern Italians descended from? ›

Finally, Southern Italians were found to present genetic affinity with populations from the Eastern Mediterranean and particularly from Crete, Cyprus, and the Anatolian/Dodecanese islands [17], with people from Sicily also showing increased proportion of ancestry components likely introduced during the Arab occupation ...

What is the history of Italy north vs South? ›

The Arabs, Greeks and Spanish ruled southern Italy while the French, Celts and Germanic tribes ruled the North. Because of this, the culture, customs and cuisines were highly influenced by these different countries, though the term is often used lightly in conversation, it continues to create a divide between regions.

What are the origins of northern Italians? ›

The first modern inhabitants of the area recognized as Northern Italy were primarily of Celtic origin. These groups of people arrived to the area around 600 B.C, according to most historians. What is this? Yes, Celts in Italy.

Why have many Italians migrated to the north in recent years? ›

Why have Italians migrated to the North in recent years? To look for jobs because the north is much more industrialized than the south.

Are Italians genetically descended from Romans? ›

So, do modern Italians come from the Romans? Well, yes, of course: but the Romans were a genetically mixed bunch and so were medieval Italians, who are closer ancestors to us than them. That's why we can say we are, today, as genetically varied and beautiful as varied and beautiful is the land we come from!

What are people from southern Italy called? ›

Terrone (Italian pronunciation: [terˈroːne]; plural terroni, feminine terrona) is an Italian term to designate, in an often pejorative manner, people who dwell in Southern Italy or are of Southern Italian descent.

What country has the most Italian descendants? ›

Italian Brazilians are Brazilian citizens of full or partial Italian descent. Italian Brazilians are the largest number of people with full or partial Italian ancestry outside Italy, with São Paulo being the most populous city with Italian ancestry in the world.

Who unified northern and southern Italy? ›

Garibaldi fought for Italian unity and almost single-handedly united northern and southern Italy. He led a volunteer army of guerrilla soldiers to capture Lombardy for Piedmont and later conquered Sicily and Naples, giving southern Italy to King Victor Emmanuel II of Piedmont, who established the Kingdom of Italy.

What are northern Italians known for? ›

Northern Italy is also known for being the home of balsamic vinegar, the most expensive white truffles, several varieties of risotto rice, and is home to Piedmontese cattle which is one of the most prized in the world.

Where did Italians first come from? ›

Prior to 1900 the majority of Italian immigrants were from northern and central Italy. Two-thirds of the migrants who left Italy between 1870 and 1914 were men with traditional skills. Peasants were half of all migrants before 1896.

Where did most Italians come from? ›

Between around 1880 and 1924, more than four million Italians immigrated to the United States, half of them between 1900 and 1910 alone—the majority fleeing grinding rural poverty in Southern Italy and Sicily. Today, Americans of Italian ancestry are the nation's fifth-largest ethnic group.

When did Italians first migrate to America? ›

Italian immigrants began arriving in large numbers in the late 1800s as relatively unskilled labor that helped fuel a booming industrial economy.

Where did most Italian immigrants to America come from? ›

The peak period of Italian immigration to the United States occurred between 1880 and 1921, when approximately 4.2 million Italians came to America. The vast majority of these immigrants, about 80 percent, hailed from the Mezzogiorno in southern Italy, a region in the midst of great tumult and hardship.

Who were the first Italian immigrants to America? ›

The first sizable Italian immigration to North America involved certain religious refugees, the Waldensians, who migrated from Holland in 1657. About 167 Waldensians were brought over and settled in New Castle, Delaware, as well as in New Amsterdam.

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