Hypophosphatemia in Emergency Medicine Treatment & Management: Emergency Department Care (2024)

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Hypophosphatemia in Emergency Medicine Treatment & Management: Emergency Department Care (2024)

FAQs

Hypophosphatemia in Emergency Medicine Treatment & Management: Emergency Department Care? ›

Management of hypophosphatemia

What is the treatment for hypophosphatemia? ›

Healthcare providers most often use oral phosphate replacement medication (pills taken by mouth) to treat mild to moderate cases of hypophosphatemia. They may also recommend eating foods high in phosphorus to correct your phosphate levels. If hypophosphatemia is severe, they provide phosphate replacement through an IV.

What is the most common cause of hypophosphatemia in hospitalized patients? ›

Surgery, followed by a period of fasting with intravenous administration of glucose, and gram-negative septicemia are the most common causes.

What findings can be expected with hypophosphatemia? ›

Normal blood phosphorous levels are between 2.5 to 4.5 mg/dL. Hypophosphatemia is a condition in which your blood has a low level of phosphorous. Low levels can cause a host of health challenges, including muscle weakness, respiratory or heart failure, seizures, or comas.

What would a patient with hypophosphatemia exhibit? ›

Mild hypophosphatemia (ie, 2-2.5 mg/dL), whether acute or chronic, is generally asymptomatic. Patients with severe and/or chronic hypophosphatemia are more likely to be symptomatic. Weakness, bone pain, rhabdomyolysis, and altered mental status are the most common presenting features.

What foods help hypophosphatemia? ›

Eat more foods that contain phosphorus.
  • Increase your intake of milk, cream, cheese, cottage cheese, yogurt, puddings, custard, and ice cream. Add powdered milk to foods.
  • Eat meat, fish, poultry, eggs, and peanuts and other nuts and seeds. ...
  • Eat bran cereal, granola, oatmeal, and wheat germ.

What happens when phosphorus is too low? ›

Symptoms of phosphorus deficiency include loss of appetite, anxiety, bone pain, fragile bones, stiff joints, fatigue, irregular breathing, irritability, numbness, weakness, and weight change. In children, decreased growth and poor bone and tooth development may occur.

Is hypophosphatemia life threatening? ›

Acute severe hypophosphatemia can be life threatening and is associated with mortality and impaired cardiac and respiratory function.

What is the critical illness hypophosphatemia? ›

Hypophosphatemia can be found in patients with severe infections, such as sepsis. Especially patients with Gram-negative bacteremia may develop hypophosphatemia [9]. Hypophosphatemia correlates to severity of illness and can even be used as a prognostic parameter in sepsis patients [10].

What drugs can cause hypophosphatemia? ›

The following may cause hypophosphatemia: Alcoholism. Antacids. Certain medicines, including insulin, acetazolamide, foscarnet, imatinib, intravenous iron, niacin, pentamidine, sorafenib, and tenofovir.

How do you fix low phosphorus? ›

The best way to increase phosphorus levels in the blood is to eat a phosphorus-rich diet. Protein-rich foods are high in phosphorus, which is present in almost all food sources because it is an essential component of all living organisms.

Can hypophosphatemia cause anxiety? ›

Panic attacks have been associated with hypophosphatemia in numerous case reports, and hypophosphatemia has even been proposed as a biomarker for panic disorder,14 with serum phosphate levels being negatively correlated with anxiety level.

What foods should I avoid if my phosphorus is low? ›

Limit the phosphorus-rich foods like dried beans, black-eyed peas and organ meats, such as chitterlings/chitlins. Use nondairy creamers and milk substitutes in place of milk in cereals, coffee, and many sauces. Serving size is very important because most foods have phosphorus.

How do you treat severe hypophosphatemia? ›

Severe hypophosphatemia (< 1.0 mg/dL [0.3 mmol/L]) in critically ill, intubated patients or in those with clinical sequelae of hypophosphatemia (eg, hemolysis) should be managed with intravenous replacement therapy (0.08–0.16 mmol/kg) over 2-6 hours.

What level is severe hypophosphatemia? ›

Hypophosphatemia is defined as mild (2-2.5 mg/dL, or 0.65-0.81 mmol/L), moderate (1-2 mg/dL, or 0.32-0.65 mmol/L), or severe (< 1 mg/dL, or 0.32 mmol/L). Mild to moderately severe hypophosphatemia is usually asymptomatic. Major clinical sequelae usually occur only in severe hypophosphatemia.

What is a rare disease associated with hypophosphatemia? ›

X-linked hypophosphatemia (XLH) is a hereditary, progressive, and lifelong rare disease that affects up to 1 in 20,000 people. XLH can affect the bones, muscles, and teeth of both children and adults. This is due to excessive loss of phosphorus.

Is there a medication to lower phosphorus? ›

Phosphate (phosphorus) binders are medications that help lower phosphate levels in your body. Phosphate is a mineral that helps with several functions in your body, but if you have too much of it in your bloodstream, it can cause problems. Your healthcare provider may recommend phosphate binders as treatment.

What is the new drug for hypophosphatemia? ›

Recently, burosumab, an antibody against FGF-23, was approved as a novel therapy for children and adults with X-linked hypophosphatemia and patients with tumor-induced osteomalacia. Burosumab showed good performance in different trials in children and adults.

What supplements are good for hypophosphatemia? ›

Vitamin D supplementation

These patients benefit from oral 1,25 dihydroxyvitamin D3 supplements. Because vitamin D enhances calcium and phosphate absorption, frequent monitoring of both is required.

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