Diagnosis of Gastroparesis - NIDDK (2024)

How do doctors diagnose gastroparesis?

Doctors diagnose gastroparesis based on your medical history, a physical exam, your symptoms, and medical tests. Your doctor may also perform medical tests to look for signs of gastroparesis complications and to rule out other health problems that may be causing your symptoms.

Medical history

Your doctor will ask about your medical history. He or she will ask for details about your current symptoms and medicines, and current and past health problems such as diabetes, scleroderma, nervous system disorders, and hypothyroidism.

Your doctor may also ask about

Physical exam

During a physical exam, your doctor will

Diagnosis of Gastroparesis - NIDDK (1)

What medical tests do doctors use to diagnose gastroparesis?

Doctors use lab tests, upper gastrointestinal (GI) endoscopy, imaging tests, and tests to measure how fast your stomach is emptying its contents to diagnose gastroparesis.

Lab tests

Your doctor may use the following lab tests:

Upper GI endoscopy

Your doctor may perform an upper GI endoscopy to look for problems in your upper digestive tract that may be causing your symptoms.

Imaging tests

Imaging tests can show problems, such as stomach blockage or intestinal obstruction, that may be causing your symptoms. Your doctor may perform the following imaging tests:

Tests to Measure Stomach Emptying

Your doctor may perform one of more of the following tests to see how fast your stomach is emptying its contents.

  • Gastric emptying scan, also called gastric emptying scintigraphy. For this test, you eat a bland meal—such as eggs or an egg substitute—that contains a small amount of radioactive material. A camera outside your body scans your abdomen to show where the radioactive material is located. By tracking the radioactive material, a health care professional can measure how fast your stomach empties after the meal. The scan usually takes about 4 hours.
  • Gastric emptying breath test. For this test, you eat a meal that contains a substance that is absorbed in your intestines and eventually passed into your breath. After you eat the meal, a health care professional collects samples of your breath over a period of a few hours—usually about 4 hours. The test can show how fast your stomach empties after the meal by measuring the amount of the substance in your breath.
  • Wireless motility capsule, also called a SmartPill. The SmartPill is a small electronic device that you swallow. The capsule moves through your entire digestive tract and sends information to a recorder hung around your neck or clipped to your belt. A health care professional uses the information to find out how fast or slow your stomach empties, and how fast liquid and food move through your small intestine and large intestine. The capsule will pass naturally out of your body with a bowel movement.

This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases(NIDDK), part of the National Institutes of Health. NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts.

The NIDDK would like to thank:
Michael Camilleri, M.D., Mayo Clinic, Rochester

Diagnosis of Gastroparesis - NIDDK (2024)

FAQs

Diagnosis of Gastroparesis - NIDDK? ›

Diagnosis. Doctors diagnose gastroparesis based on your medical history, a physical exam, symptoms, and medical tests, such as tests to measure stomach emptying. Your doctor may use medical tests to look for gastroparesis complications.

What is the best diagnostic test for gastroparesis? ›

Scintigraphy. This is the most important test used in making a diagnosis of gastroparesis. It involves eating a light meal, such as eggs and toast, that contains a small amount of radioactive material.

How does EGD diagnose gastroparesis? ›

A scan is taken right away and then every hour after the meal is ingested for up to four hours. Your medical team will evaluate how the food you ingested moves through your stomach and gastrointestinal tract. A gastric emptying test may show a delay in emptying, which can help your doctors to make the diagnosis.

What is the gold standard for diagnosing gastroparesis? ›

Gastric emptying scintigraphy (GES) is a nuclear medicine imaging test used to measure the rate of gastric emptying and is considered the “gold standard” to establish the diagnosis of gastroparesis. It is done by tracking a radioactive tracer, such as Technetium-99m (99mTc), as it moves through a patient's stomach.

What can be mistaken for gastroparesis? ›

Gastroparesis and functional dyspepsia are 2 of the most common gastric neuromuscular disorders. These disorders are usually confused, having both similarities and differences.

What is the 4 hour test for gastroparesis? ›

During this test: You will eat a meal or drink a liquid that contains a type of protein that your body absorbs. The substance eventually passes into your breath. A provider will collect samples of your breath over a period of about four hours.

Is gastroparesis overdiagnosed? ›

Summary: Gastroparesis is frequently over-diagnosed and incorrectly diagnosed. Performing a proper gastric emptying study which adheres to standard protocol, and accurately interpreting the results in the context of the individual patient, are critical to making an accurate diagnosis of GP.

Do you poop normally with gastroparesis? ›

Gastroparesis patients have a high rate of slow transit constipation by radiopaque marker studies than patients with symptoms of gastroparesis with normal gastric emptying (4). Fourth, perhaps constipation and delayed colonic transit could be the primary problem with a secondary delay in gastric emptying.

Can they see gastroparesis in an endoscopy? ›

What medical tests do doctors use to diagnose gastroparesis? Doctors use lab tests, upper gastrointestinal (GI) endoscopy, imaging tests, and tests to measure how fast your stomach is emptying its contents to diagnose gastroparesis.

What is the first line of treatment for gastroparesis? ›

Initial management of gastroparesis consists of dietary modification, optimization of glycemic control and hydration, and in patients with continued symptoms, pharmacologic therapy with prokinetic and antiemetics.

What is considered mild gastroparesis? ›

Mild Gastroparesis: In this stage, the stomach may empty slowly, but the symptoms are relatively mild and may not significantly impact daily life. Moderate Gastroparesis: The emptying of the stomach is further delayed, and symptoms become more noticeable, affecting eating patterns and causing discomfort.

What does gastroparesis pain feel like? ›

severe pain or cramping in your abdomen. blood glucose levels that are too high or too low. red blood in your vomit, or vomit that looks like coffee grounds. sudden, sharp stomach pain that doesn't go away.

How bad can gastroparesis get? ›

In severe cases, gastroparesis can result in difficulty absorbing essential nutrients from foods, key ingredients from medications, as well as dehydration.

Why do I suddenly have gastroparesis? ›

Sometimes it's a complication of diabetes, and some people develop gastroparesis after surgery. Certain medications, such as opioid pain relievers, some antidepressants, and high blood pressure and allergy medications, can lead to slow gastric emptying and cause similar symptoms.

What does your stomach feel like with gastroparesis? ›

You may feel full almost immediately and for a long time after eating. You may have a stomachache, feel nauseous or throw up. Your stomach may feel bloated or distended (stretched) and you may have acid reflux as a side effect. When stomach acid backwashes into your esophagus, it can feel like heartburn.

Do you ever feel hungry with gastroparesis? ›

You may not feel hungry and may constantly feel that your stomach is full even when you've eaten very little. You may feel uncomfortably full after eating only a small amount of food.

What is the best imaging for gastroparesis? ›

Gastric emptying scan, also called gastric emptying scintigraphy.

What is the new procedure for gastroparesis? ›

Gastric peroral endoscopic myotomy (G-POEM) is a type of submucosal endoscopy or third space endoscopy that targets the pylorus muscle to treat gastroparesis. G-POEM was derived from peroral endoscopic myotomy (POEM), which targets the lower esophageal sphincter to treat achalasia.

Does gastroparesis show up on a CT scan? ›

Abdominal CT scan may be helpful in the diagnosis of gastroparesis. Abdominal CT scan is used to rule out underlying causes and complications such as obstruction, malignancy, inflammation, infections, and other causes of abdominal pain.

What is the first line treatment for gastroparesis? ›

Initial management of gastroparesis consists of dietary modification, optimization of glycemic control and hydration, and in patients with continued symptoms, pharmacologic therapy with prokinetic and antiemetics.

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