Cymbalta vs Tramadol Comparison - Drugs.com (2024)

FAQs

Cymbalta vs Tramadol Comparison - Drugs.com? ›

Cymbalta has an average rating of 6.3 out of 10 from a total of 1873 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. Tramadol has an average rating of 7.0 out of 10 from a total of 1839 ratings on Drugs.com.

Taking tramadol with other painkillers

Some everyday painkillers that you can buy from pharmacies contain codeine, which is a similar medicine to tramadol. Codeine-containing painkillers that you can buy from pharmacies These include co-codamol, Nurofen Plus and Solpadeine.

Lexapro. Lexapro (escitalopram) is an alternative to Cymbalta that might be good for people who are concerned about Cymbalta's effects when used long-term. Lexapro is in the class of drugs called selective serotonin reuptake inhibitors (SSRIs), which work by increasing serotonin levels in the brain to enhance mood.

For a medication to be classed as an opioid, it must bind to the opioid receptors somewhere in the body. Duloxetine does not; thus, the Cymbalta drug class is not opioid. However, the lower rate of addiction and price can make it an excellent alternative to opioid medications for those dealing with nerve pain.

Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremor, ...

Duloxetine affects the voltage dependence of sodium channels in the central nervous system and peripheral nervous system (PNS) [7]. Tramadol is a mu opioid receptor analgesic with weak central effects [8]. It has a unique mechanism of action and pharmacological effects that are different from those of other opioids.

Dual action antidepressants mirtazapine (Remeron), duloxetine (Cymbalta), and most notably venlafaxine (Effexor), which tramadol is closely related to in structure, also inhibit NE and 5HT reuptake.

When comparing Cymbalta vs Lexapro for depression or anxiety, both are highly effective medication options for some people. Research suggests that Lexapro might be better tolerated and more effective when treating depression on a short-term plan.

Based on how the drug works, some people find Cymbalta to be “activating” and makes them feel energized. If this is how Cymbalta works for you, taking your dose in the morning may help ease insomnia. On the other hand, if you find that taking Cymbalta makes you sleepy, you can try taking your dose at night.

Anticonvulsants are one of the most effective medications for treating nerve pain. Examples include pregabalin (Lyrica) and gabapentin (Neurontin). These medications are typically very effective in treating nerve pain, but they may also cause undesired side effects, such as: lethargy.

What is the downside of Cymbalta? ›

Downsides

Drowsiness, insomnia, nausea, headache, dry mouth, constipation, and dizziness. Most people experience side effects with Cymbalta and one in six people stop taking the drug because of them. Severe skin reactions and urinary retention have also been reported with Cymbalta.

Duloxetine is safe, effective, and well-tolerated at doses comprised between 60 and 120 mg/day, even in elderly patients or in those with concomitant illnesses.

Both Cymbalta and Xanax can be used to treat generalized anxiety disorder (GAD). In certain situations, your doctor may prescribe Cymbalta in combination with Xanax. This is because it can take several weeks for Cymbalta to ease the symptoms of anxiety.

Examples of affected drugs include antiarrhythmic drugs (such as propafenone, flecainide, quinidine), antipsychotics (such as thioridazine), tricyclic antidepressants (such as desipramine, imipramine), among others. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction.

Common side effects include nausea, dry mouth, and drowsiness. Some people who take it describe feeling “more grounded” and in control of their emotions. Others say the medication numbed their feelings more than they expected.

Some recreational drugs, such as cannabis, will also increase tramadol side effects such as feeling sleepy and dizzy. If you take MDMA (ecstasy), cocaine, amphetamines or LSD while taking tramadol, you may develop a condition called serotonin syndrome.

Because tramadol and hydrocodone are both opioid drugs, they share similar side effects.

You may have heard the names Ultram and tramadol within the context of opioid-like prescription painkillers and wondered is Ultram the same as tramadol? Yes, Ultram is the same as tramadol. Ultram is the brand name of the generic drug tramadol.

Tramadol is a centrally acting μ-opioid receptor agonist and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Tramadol (Ultram) and codeine are both opiates and narcotics prescribed for moderate pain. Codeine is also a cough suppressant. Codeine is derived from the poppy plant like other narcotics, including morphine, heroin, and opium. Tramadol, on the other hand, is synthetic, though it is similar to codeine.