Cryotherapy for Skin Lesions (2024)

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This information explains what cryotherapy (KRY-oh-THAYR-uh-pee) is and how to care for yourself after your cryotherapy procedure. Cryotherapy is a procedure that uses extreme cold (liquid nitrogen) to freeze and destroy tissue.

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What is cryotherapy used for?

Cryotherapy is often used to treat skin lesions. Skin lesions are skin growths or patches that don’t look like the skin around them. The lesions can be:

  • Benign (not cancerous).
  • Actinic keratosis. These are precancerous skin cancers that look like scaly patches on your skin, and they can turn into cancer in the future.
  • Superficial skin cancer (skin cancer that’s on the surface of your skin).

Cryotherapy also helps save the area around the lesions and to reduce the scarring as much as possible.

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What To Expect Before and During Cryotherapy

You don’t have to do anything to get ready for cryotherapy, but you may need to take off any makeup, lotion, or powder before your procedure.

During your cryotherapy, your healthcare provider will spray liquid nitrogen on the area being treated to freeze it.

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Skin Healing After Cryotherapy

The treated area will become red soon after your procedure. It may also blister and swell. If this happens, don’t break open the blister. You may also see clear drainage on the treated area. This is normal.

The treated area will heal in about 7 to 10 days. It probably won’t leave a scar.

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How To Care for Yourself After Cryotherapy

  • Starting the day after your procedure, wash the treated area gently with fragrance-free soap and water every day.
  • Put Vaseline® or Aquaphor® on the treated area every day for 2 weeks. This will help the area heal and will keep it from crusting. If the treated area does develop a crust, you can put petroleum jelly (Vaseline) on the area until the crust falls off.
  • Leave the treated area uncovered. If you have any drainage, you can cover the area with a bandage (Band-Aid®).
  • If you have any bleeding, press firmly on the area with a clean gauze pad for 15 minutes. If the bleeding doesn’t stop, repeat this step. If the bleeding still hasn’t stopped after repeating this step, call your doctor’s office.
  • Don’t use scented soap, makeup, or lotion on the treated area until it’s fully healed. This will usually be at least 10 days after your procedure.
  • You may lose some hair on the treated area. This depends on how deep the freezing went. This hair loss may be permanent.
  • Once the treated area has healed, apply a broad-spectrum sunscreen with an SPF of at least 30 to the area to protect it from scarring.
  • You may have discoloration (pinkness, redness, or lighter or darker skin) at the treated area for up to 1 year after your procedure. Some people may have it for even longer, or it may be permanent.
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When To Call Your Doctor or Nurse

Call your doctor or nurse if you have:

  • A fever of 100.4 °F (38 °C) or higher.
  • Chills (Feeling cold and shivering).
  • Any of the following symptoms at or around the treated area:
    • Redness or swelling that extends to areas of untreated skin.
    • Increasing pain or discomfort in the treated area.
    • Skin in the treated area that’s hot or hard to the touch.
    • Increasing oozing, or drainage (yellow or green) from the treated area.
    • A bad smell.
    • Bleeding that doesn’t stop after applying pressure.
  • Any questions or concerns.
  • Any problems you didn’t expect.
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If you have any questions, contact a member of your care team directly. If you're a patient at MSK and you need to reach a provider after , during the weekend, or on a holiday, call

212-639-2000

.

If you have any questions, contact a member of your care team directly. If you're a patient at MSK and you need to reach a provider after , during the weekend, or on a holiday, call

212-639-2000

.

For more resources, visit www.mskcc.org/pe to search our virtual library.

Cryotherapy for Skin Lesions - Last updated on December 15, 2022
All rights owned and reserved by Memorial Sloan Kettering Cancer Center
Cryotherapy for Skin Lesions (2024)

FAQs

How long does it take skin to heal from liquid nitrogen? ›

If the freezing was extensive enough, a blister (or bloodblister) may develop. If blistering is severe, the area may weep for several days. Total healing varies between one and three weeks, depending on which area of the body was treated.

How does cryotherapy work for skin lesions? ›

Cryotherapy is a minimally-invasive treatment that freezes skin surface lesions using extremely cold liquid or instruments (cryogen). Cryotherapy, also known as cryosurgery or cryoablation, can be delivered with various cryogens.

Which lesions are suitable for cryotherapy? ›

Cryosurgery has a number of indications for both malignant and benign lesions. Benign lesions that can be treated with cryosurgery include seborrheic keratosis, verruca, skin tags, molluscum contagiosum, solar lentigo and hypertrophic/keloid scars.

How long does it take for lesion to fall off after cryotherapy? ›

A simple antiseptic cream such as Savlon™ may be used if the blister bursts. The blisters will form scabs that will fall off after about 2 - 3 weeks. Sometimes swelling may develop in the surrounding skin, particularly if you have an area around your eyes treated.

How do I take care of my skin after liquid nitrogen treatment? ›

How To Care for Yourself After Cryotherapy. Starting the day after your procedure, wash the treated area gently with fragrance-free soap and water every day. Put Vaseline® or Aquaphor® on the treated area every day for 2 weeks. This will help the area heal and will keep it from crusting.

How do you take care of your skin after cryotherapy? ›

It is ok to bathe normally after your treatment. Gently clean the area in the shower or bath with warm water and mild soap, then pat dry. Apply Vaseline or Aquaphor to the area 1-2x daily. You do not have to keep the area covered with a Band-Aid, but certainly can if you prefer.

What not to do after liquid nitrogen? ›

Do not soak treated area (ie, wash dishes, swim, etc) during the first 24 hours. ► You should gently cleanse the treated area daily with mild soap and water. ► If the area is excessively uncomfortable, you may take an over-the-counter pain reliever such as acetaminophen (Tylenol®) or ibuprofen (Advil®).

How many cryotherapy treatments to see results? ›

At °degree Wellness, we recommend seven to ten sessions either a few days apart or over a two to three week spread if you want to maximize and maintain your benefits.

Is skin cryotherapy painful? ›

During treatment, the pain of cryotherapy is an extremely cold, sharp, stinging sensation. This settles almost immediately to a milder pain which usually lasts a few minutes, but may persist for some hours. The treated area sometimes feels mildly irritated or itchy after this.

Who is not a good candidate for cryotherapy? ›

The following conditions are contraindications to whole body cryotherapy: Pregnancy, severe Hypertension (BP> 180/100), acute or recent myocardial infarction, unstable angina pectoris, arrhythmia, symptomatic cardiovascular disease, cardiac pacemaker, peripheral arterial occlusive disease, venous thrombosis, acute or ...

What happens when you freeze a skin lesion? ›

The liquid nitrogen needs to be applied long enough to freeze the affected skin. By freezing the skin, a blister is created underneath the lesion. Ideally, as the new skin forms underneath the blister, the abnormal skin on the roof of the blister peels off.

What are the problems with cryotherapy? ›

Besides changes in vital signs, whole-body cryotherapy can have other serious risks. These include major skin damage, such as frostbite, burns, and frozen limbs. Frozen limb is a severe type of frostbite. It causes skin blisters, swelling, and third-degree burns after warming back up.

Does skin scab after cryotherapy? ›

Swelling and/or blistering often develop within a couple of hours after treatment. 2-3 days after treatment a scab will probably form which should then take 7-10 days to fall off, leaving a pink smooth area. Occasionally there may be a slight scar left after treatment.

How long does skin stay pink after cryotherapy? ›

A sore or scab may form at the site, which should heal within 1-3 weeks. The area may be pink for several weeks and for the next few months the area may be lighter or darker than the surrounding skin. Rarely there is a permanent change to the skin color.

What color is your skin after cryotherapy? ›

The appearance of the skin after cryotherapy is usually very good. After the scab has fallen off, the fresh skin underneath will usually look slightly pink/red. This is normal, and will quite quickly blend with your natural skin tone. Rarely, hyper-pigmentation may develop over the treated area.

How long does liquid nitrogen take to scab? ›

It is normal for the blister to open up and bleed slightly and ooze a clear, slightly red or yellow fluid and be seen on the open blister or band aid until it is HEALED or scabbed up. The blister usually takes 2-4 weeks to heal.

How long does redness last after liquid nitrogen? ›

The skin around the area that was frozen may appear “puffy” and reddened for several days. You may-experience a blister or even a blood blister over the area that was frozen. The blister may last for a period of 1 to 2 weeks, and then slowly heal with crusting.

How long does it take for a scab to form after cryotherapy? ›

Swelling and/or blistering often develop within a couple of hours after treatment. 2-3 days after treatment a scab will probably form which should then take 7-10 days to fall off, leaving a pink smooth area.

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