Chronic Liver Disease (2024)

Chronic liver disease is marked by the gradual destruction of liver tissue over time. Liver diseases in this category include:

  • Cirrhosis
  • Fibrosis of the liver

Cirrhosis of the Liver

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), cirrhosis is the 12th leading cause of death in the United States.

Because of chronic damage to the liver:

  1. Scar tissue slowly replaces normal functioning liver tissue.
  2. The scar tissue progressively diminishes the blood flow through the liver.
  3. As the normal liver tissue is lost, the liver can no longer effectively process nutrients, hormones, drugs and poisons.
  4. In addition, the liver cannot effectively produce proteins and other substances.

Fibrosis of the Liver

Fibrosis is the growth of scar tissue due to infection, inflammation, injury or even healing. The overgrowth of scar tissue can occur in almost any organ. Fibrosis in the liver can prevent the organ from properly functioning. Liver fibrosis is usually the result of cirrhosis.

Cirrhosis Symptoms

Symptoms of cirrhosis include coughing up blood, hair loss and jaundice (a yellowing of the skin and eyes). Learn more about cirrhosis symptoms.

Causes of Cirrhosis

The most common cause of cirrhosis is alcohol abuse. Other causes include hepatitis and using certain drugs. Learn more about causes of cirrhosis.

Cirrhosis Diagnosis

Diagnosing cirrhosis includes a physical examination as well as other, specialized test such as liver function tests and a liver biopsy. Learn more about cirrhosis diagnosis.

Cirrhosis Treatments

Liver damage is irreversible. Treatments focus on preventing further damage. Learn more about cirrhosis treatments, including liver transplant.

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Chronic Liver Disease
We offer comprehensive diagnosis and treatment for chronic liver diseases, including cirrhosis.
Chronic Liver Disease

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Chronic Liver Disease (2024)

FAQs

Chronic Liver Disease? ›

Chronic liver disease represents a continuous and progressive process of hepatic fibrosis, liver tissue architectural distortion, and regeneration nodule formation. While fibrosis is usually irreversible, but it can be reversible in the initial stage of development.

Can you live with chronic liver disease? ›

In the early stages of compensated cirrhosis, life expectancy may still be upwards of 15 years. When portal hypertension develops, it reduces that expectancy, primarily due to the risk of internal bleeding it can cause. Decompensated cirrhosis has an average life expectancy of seven years.

Can chronic liver disease be treated? ›

This depends on the cause and how treatable it is. Once you have cirrhosis, you can't undo the scarring that's already been done, but you may be able to prevent further damage or slow it down. Chronic liver failure isn't reversible, though it can still take years to progress.

What are the signs your liver is shutting down? ›

Acute liver failure can develop quickly in an otherwise healthy person, and it is life-threatening. If you or someone you know suddenly develops a yellowing of the eyes or skin; tenderness in the upper abdomen; or any unusual changes in mental state, personality or behavior, seek medical attention right away.

What are the three worst things for your liver? ›

Foods that are high in sugar, fat, and salt put extra stress on the liver. Fast food, packaged foods, and processed foods tend to contain a lot of these elements.

What is Stage 1 liver failure? ›

Stage 1 is inflammation of your liver, caused by your immune system reacting to a foreign substance, like toxins. Chronic inflammation can lead to an enlarged liver. Inflammation can result from fatty liver, hepatitis, and other causes. Stage 2 is liver fibrosis or liver scarring, caused by chronic inflammation.

How fast does chronic liver disease progress? ›

Liver failure can develop slowly or rapidly, depending on the cause and the condition of the liver. Chronic liver failure: The most common type of liver failure is chronic, which can take months or years to develop.

Is chronic liver disease a terminal illness? ›

This is called liver failure. Cirrhosis can be fatal if the liver fails. However, it usually takes years for the condition to reach this stage and treatment can help slow its progression. Each year in the UK, around 4,000 people die from cirrhosis and 700 people with the condition need a liver transplant to survive.

How does your body warn you that liver disease is forming? ›

If there are symptoms of liver disease, they may include: Yellowing of the skin and the whites of the eyes, called jaundice. Yellowing of the skin might be harder to see on Black or brown skin. Belly pain and swelling.

How do I make my liver healthy again? ›

How to improve liver health naturally
  1. Know your risk factors for liver issues. Talk with your primary care provider about your potential risk factors for liver disease. ...
  2. Watch your alcohol intake. Dr. ...
  3. Don't drink while taking certain medications. ...
  4. Avoid overuse or incorrect use of medications. ...
  5. Maintain a healthy lifestyle.
Jan 16, 2024

What part of the body itches with liver problems? ›

Symptoms of itching with liver disease

Some people may itch in one area, such as a limb, the soles of their feet, or the palms of their hands, while others experience an all-over itch. Itching linked to liver disease doesn't generally involve rash or skin lesions.

What are the four warning signs of a dying liver? ›

The most common symptoms are jaundice, nausea, fatigue, and pain on the right side of the abdomen. If you think you may be experiencing signs of liver disease, see a healthcare provider right away. National Institute of Diabetes and Digestive and Kidney Disease.

What does liver disease fatigue feel like? ›

Fatigue may occur at any time of day but is most common in the morning about an hour after awakening. By 9 a.m. one may already feel the exhaustion of a full workday. Others describe weakness and a lack of energy throughout the entire day. Their usual "pep" is now gone.

How long does chronic liver disease last? ›

Chronic liver disease (CLD) is a progressive deterioration of liver functions for more than six months, which includes synthesis of clotting factors, other proteins, detoxification of harmful products of metabolism, and excretion of bile.

Is chronic liver disease life threatening? ›

Your liver may keep working even when you have cirrhosis. However, cirrhosis can eventually lead to liver failure, and you can get serious complications, which can be life threatening.

What is the mortality rate for chronic liver disease? ›

Typically, liver cirrhosis and other chronic liver diseases develops following prolonged inflammation. The mortality and morbidity associated with liver cirrhosis and other chronic liver diseases increase sharply, with a 1-year case-fatality rate reaching up to 80%.

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